Chapter 16: An experiment with five controllable factors in eight different arrangements. Col 1: Factor A level Col 2: factor B level Col 3: Factor C level Col 4: Factor D level Col 5: Factor E level Cols 6-10 : Observed responses for the combinations of A-E. - - - + + 4.5 9.0 0.5 5.0 3.5 + - - - - 9.5 8.0 3.5 7.0 4.5 - + - - + 0.5 4.0 1.5 6.0 7.0 + + - + - 11.5 9.5 6.6 17.5 9.5 - - + + - 7.0 8.5 19.5 15.5 16.0 + - + - + 2.5 5.0 1.0 7.0 4.5 - + + - - 9.0 13.5 0.5 5.5 7.0 + + + + + 10.5 4.5 4.0 1.5 2.5